His visual acuity was 6/ 9 in RE improving to 6/ 6 with 0.5 Dcyl at 800 and 6/ 6 in the left eye. Consent was taken from the patient for examination and use of images, and health data for the purpose of research and publication. Institutional ethical clearance was taken for the study and it adhered to the 1975 Helsinki Declaration, as revised in 20. He denied any history of trauma or surgery. This report describes for the first time the optical density (OD) of an anterior chamber iris cyst using optical coherence tomography (OCT) and ImageJ software.Ī 26-year-old male presented with complaints of blurring of vision in his right eye (RE) for past two months without any other ocular complaints. ImageJ software has been used in retinal images to characterize the optical density of subretinal fluid in various retinal diseases. The clinical and morphological features of such cysts are well characterized however, the optical properties of the contents are not well documented. At times, these mass lesions have been mistaken for malignancy, and literature has few reports of enucleation performed for the fear of malignancy.
Usually, these cysts remain asymptomatic, but can lead to complications due to inflammation, glaucoma, or mass effect. They can be free-floating in the anterior chamber or fixed to anatomical structures. These cysts are lined with pigment epithelium and contain clear fluid. Iris cysts in the anterior chamber have been well described in literature. The iris pigmented cysts can present at the pupillary margin, posterior layers of iris epithelium or free-floating in aqueous or vitreous. Additionally, based on the location, cysts can be central, middle, or peripheral in relation to the pupil. Epithelial cysts arise from layers of pigmented epithelium of the iris. Primary iris cysts are clinically classified as epithelial and stromal subtypes. The aetiology of primary iris cysts is poorly understood, whereas secondary cysts have an antecedent cause like the use of miotics, trauma or surgery. Iris cysts have always fascinated ophthalmologists because of rarity of occurrence and mystery about their origin.
The innovative use of an OCT image and the ImageJ software to determine the optical density of the iris cyst may aid in the diagnosis and follow-up of such cases. The OD of cyst fluid was found comparable to the anterior chamber fluid.Ĭonclusion: Ultrasound biomicroscopy (UBM) and OCT are useful tools for the diagnosis of cystic lesions of the anterior segment.
#Imagej software densitometry code#
Results: The optical density (OD) of the cyst fluid was determined using ImageJ, an open code Java-based image processing software. Anterior segment optical coherence tomography (OCT) revealed a cystic lesion with hyperreflective walls and hypo reflective lumen attached to the cornea, compressing the endothelium. On slit lamp examination, a small translucent pigmented cyst was noted inferiorly in the anterior chamber, struck on to the cornea at 6 o’clock periphery, without any feeder vessel. His visual acuity was 6/ 9 on Snellen’s chart. Method: A 26-year-old male presented with blurring of vision in his right eye for two months, without any other associated ocular complaints. Aim: To report the optical characteristics of the fluid in an anterior chamber iris cyst.
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